Sharapova, competing for the first time since retiring from her first-round match at Wimbledon, appeared to be on course for just a fourth match win since January when she went up a set and an early break on the 16th seed from Estonia.
England's record wicket-taker broke down after just four overs in the series opener at Edgbaston and did not bowl again as Australia romped to a 251-run victory.
Joe Root insisted England would avoid pressing the panic button after going 1-0 down in the Ashes with a crushing 251-run defeat in the first Test at Edgbaston.
Sebastian Vettel came home third ahead of team-mate Charles Leclerc, but both conceded that they could not generate the pace to compete with Hamilton's Mercedes or the Red Bull of second-placed Max Verstappen at the Hungaroring.
There are few weaknesses in City's balanced squad, which combines title-winning nous with an enviable depth of talent.
The Argentina star has already been ruled out of the team's trip to Florida for a one-off friendly against Napoli in Miami on Wednesday.
Dale Steyn’s retirement brought to an end one of the great fast bowling Test careers of the modern era.
Last season's top three in the PSL Mamelodi Sundowns, Orlando Pirates and Bidvest Wits all got their 2019/20 seasons off to the perfect start.
The embarrassing loss completed a chaotic week for South African football with England-born national coach Stuart Baxter quitting two days ago.
Manchester City won the Community Shield with a 5-4 penalty shoot-out win over Liverpool after a 1-1 draw at Wembley on Sunday.
